Obesity is a major health risk that is increasing in frequency. It is associated with several adverse health risks such as adult- onset diabetes, cardio- vascular disease, and hypertension. In the US today, over 25% of women in the reproductive age are obese and in Mexico, that number is closer to 50%. Considering how frequently obesity occurs and the serious health consequences of being obese, it is surprising (and for those of us with weight-control issues, it is infuriating) that there are no successful long-term treatments for obesity. So, who is considered “obese?” Obesity is an excess body weight for a given height. Body mass index (BMI) is the most frequently measurement used to define obesity. A BMI (Weight in kg/ height in m2) of over 25 is considered overweight, over 30 -34 obese class 1, 35-39 obese class 2, and > 39 as obese class 3 (sometimes referred to a morbidly obese). A 5’5” woman weighing 130 pounds has a BMI of 21.6. A woman of the same height weighing 150 has a BMI of 25 and is considered overweight.
The recently published study demonstrated that diet was significantly related to improvements in insulin resistance. Arguably, improving insulin resistance could reduce intra-ovarian androgens. This may create a more normal physiology, which could significantly improve pregnancy rates.
(1)Yujie Shang, Huifang Zhou, Minghui Hu, Hua Feng, Effect of Diet on Insulin Resistance in Polycystic Ovary Syndrome, The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 10, October 2020, Pages 3346–3360, https://doi.org/10.1210/clinem/dgaa425
(2)Espinós JJ, Polo A, Sánchez-Hernández J, Bordas R, Pares P, Martínez O & Calaf J. Weight decrease improves live birth rates in obese women undergoing IVF: a pilot study. Reproductive BioMedicine Online 2017 35 417–424. https://doi.org/10.1016/j. rbmo.2017.06.019 10
Dr. John Rinehart MD, Ph.D. has been trained in both reproductive endocrinology and andrology at Brigham and Women’s Hospital of the Harvard Medical School. Dr. Rinehart is accepting new patients in his practices at the Oak Lawn (630-366-5100) and Hinsdale (630-366-5100) offices.